olive leaf extract anticancer 
JC73
13 y
5,238
Source
Department of Immunology, Institute for Biological Research, Belgrade University, Belgrade, Serbia. sanjamama@yahoo.com
Abstract
Various constituents of the olive tree (Olea europaea) have been traditionally used in the treatment of infection, inflammation, prevention of chronic diseases, cardiovascular disorders and cancer. The anticancer potential of dry olive leaf extract (DOLE) represents the net effect of multilevel interactions between different biologically active compounds from the extract, cancer cells and conventional therapy. In this context, it was of primary interest to evaluate the influence of DOLE on progression of the highly malignant, immuno- and chemoresistant type of skin cancer-melanoma. DOLE significantly inhibited proliferation and subsequently restricted clonogenicity of the B16 mouse melanoma cell line in vitro. Moreover, late phase tumor treatment with DOLE significantly reduced tumor volume in a syngeneic strain of mice. DOLE-treated B16 cells were blocked in the G(0) /G(1) phase of the cell cycle, underwent early apoptosis and died by late necrosis. At the molecular level, the dying process started as caspase dependent, but finalized as caspase independent. In concordance, overexpression of antiapoptotic members of the Bcl-2 family, Bcl-2 and Bcl-XL, and diminished expression of their natural antagonists, Bim and p53, were observed. Despite molecular suppression of the proapoptotic process, DOLE successfully promoted cell death mainly through disruption of cell membrane integrity and late caspase-independent fragmentation of genetic material. Taken together, the results of this study indicate that DOLE possesses strong antimelanoma potential. When DOLE was applied in combination with different chemotherapeutics, various outcomes, including synergy and antagonism, were observed. This requires caution in the use of the extract as a supplementary antitumor therapeutic.
Copyright © 2010 UICC.
PMID:
20568104
[PubMed - indexed for MEDLINEAdvertisement
9 Day Fasting Program
Complete with herbs and clay to eliminate hunger and cleansing reactions.
- Re: olive leaf extract anticancer mo123
13 y
4,956
This is a reply to # 1,857,896One woman here on curezone and you can do a search cured her cancer with fresh olive leaf. She filled a blender half way up with fresh leaves and kept adding water until the water filled the blender,blending slowly each time.
It took her 9 months but her cancer was gone. Keep in mind that this mixture taste absolutely awful. I dry fresh leaves and blend them with fennel seeds to make them easy to place in capsules and prescribe my patients to take 21 the first day all at once and then 9 each day after that. They are miracle drugs but as the article states is just part of an anti cancer ritual.
Sara- Re: olive leaf extract anticancer JC73
13 y
4,846
This is a reply to # 1,857,910Looks like olive leaf is also anti-viral.I wonder if its possible to take too many antiviral supplements?
http://www.ncbi.nlm.nih.gov/pubmed/15869811
- Re: olive leaf extract anticancer JC73
13 y
5,020
This is a reply to # 1,858,177Advertisement
9 Day Fasting Program
Complete with herbs and clay to eliminate hunger and cleansing reactions.
Sorry to keep adding but I am finding all kinds of good research on olive leaf.What does it not do?
"Antihypertensive, antiatherosclerotic and antioxidant activity of triterpenoids isolated from Olea europaea, subspecies africana leaves.
Somova LI, Shode FO, Ramnanan P, Nadar A.
Source
Department of Human Physiology, University of Durban-Westville, Private Bag X54001, Durban 4000, South Africa. somova@pixie.udw.ac.za
Abstract
For the first time a biossay-directed study of triterpenoids isolated from the leaves of Olea europaea from Greece, from wild African olive and from a cultivar of O. europaea grown in Cape Town was reported. The experiment was undertaken since our preliminary analyses showed that the African wild olive leave is rich in triterpenoids and contain only traces of the glycoside oleuropein, which is typical for the European olive leaves. The isolate of the African wild olive leaves (AO) used in the experiments was found to contain 0.27% 1:1 mixture of oleanolic acid and ursolic acid, named oleuafricein. The isolate of Greek olive leaves (GO) was found to contain 0.71% oleanolic acid, and the Cape Town cultivar (CT) contained 2.47% oleanolic acid. No ursolic acid was found in either GO or CT. The antihypertensive, diuretic, antiatherosclerotic, antioxidant and hypoglycemic effects of authentic oleanolic and ursolic acid and the three isolates (GO, AO and CT) were studied on Dahl salt-sensitive (DSS), insulin-resistant rat genetic model of hypertension. All three isolates, in a dose 60 mg/kg b.w. for 6 weeks treatment, prevented the development of severe hypertension and atherosclerosis and improved the insulin resistance of the experimental animals. GO, OA and CT isolates could provide an effective and cheap treatment of this particular, most common type of salt-sensitive hypertension in the African population.
Copyright 2002 Elsevier Science Ireland Ltd.
PMID:
12648829
[PubMed - indexed for MEDLINE] "
- Re: olive leaf extract anticancer JC73
13 y
5,020
- Re: olive leaf extract anticancer JC73
13 y
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- Re: olive leaf extract anticancer Hveragerthi
13 y
5,632
MoreThis is a reply to # 1,857,896
Another way olive leaf helps to fight cancer is through its antiviral activity/. Keeping in mind that most cancers have been linked to viral infections.
Long before olive leaf became popular in the AIDS community to fight HIV, also a cancer virus, olive leaf's primary use was as a sedative, meaning it could also help with things such as high blood pressure as well. The AIDS community then discovered that olive leaf was also a source of natural protease inhibitors that inactivated viruses like HIV, formerly known as human T-cell leukemia/lymphoma virus type 3 (HTLV-3). A few years later olive leaf started being promoted for many other conditions such as various infections.
- Re: olive leaf extract anticancer happyfamily6
13 y
4,769
MoreThis is a reply to # 1,858,869Is olive leaf more antiviral than andrographis? If I'm coming down with a virus, the first thing I start taking is andrographis. Is olive leaf good to take as well, or just overkill?
:)
Diana- Re: olive leaf extract anticancer Hveragerthi
13 y
5,194
This is a reply to # 1,859,004Advertisement
9 Day Fasting Program
Complete with herbs and clay to eliminate hunger and cleansing reactions.
Is olive leaf more antiviral than andrographis?
I think andrographis is much stronger than olive leaf.
If I'm coming down with a virus, the first thing I start taking is andrographis. Is olive leaf good to take as well, or just overkill?
I would not take it with the andrographis due to the high tannin content of olive leaf.
- Re: olive leaf extract anticancer #116107
13 y
5,028
This is a reply to # 1,859,216Perhaps this is a very stupid question, but if cancer is caused by viruses, is it contageous... like a flu or cold? Can you explain a bit what a "cancer virus" is, and how they are formed in us? Thank you!
- Re: olive leaf extract anticancer Hveragerthi
13 y
5,267
This is a reply to # 1,859,247
Perhaps this is a very stupid question, but if cancer is caused by viruses, is it contageous... like a flu or cold?
Technically yes. Cancer viruses are transmissible. For example, HPV viruses can be spread by contact or sexua| intercourse. Hepatitis viruses can be spread through several means as well. And the HIV virus is believed to be spread through various means including mosquito and bedbugs, which have been shown to carry the virus. HIV is actually a leukemia/lymphoma virus, which is interesting since the first leukemia virus, from chickens, was found to be airborne transmitted. But transmission does not mean chronic infection, nor the production of cancer. These require sufficiently suppressed immune systems to allow the viruses to take hold and cause problems such as cancer. Same principle as how you can be around someone with a cold or flu and not develop that cold or flu yourself. Viruses require immune suppression to take hold in a person's body.
Can you explain a bit what a "cancer virus" is, and how they are formed in us? Thank you!
In short, viruses are genetic material (RNA or DNA) encapsulated by a protein or lipid (fatty) coating. Viruses cannot replicate though without a host cell. Once inside the cell viruses can use the cell to set up a "factory" with the cell's genes to produce copies of itself.
Cancer viruses are simply viruses that can cause cancer. Once they insert their genetic material in to the genetic material of another cell they can create mutations that lead to the formation of cancer.
- Re: olive leaf extract anticancer Hveragerthi
13 y
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- Re: olive leaf extract anticancer #116107
13 y
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- Re: olive leaf extract anticancer Hveragerthi
13 y
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- Re: olive leaf extract anticancer happyfamily6
13 y
4,769
- Re: olive leaf extract anticancer mo123
13 y
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