Lyme disease is tested by WB blood test. There are some labs that specialize in it and are more accurate than others since the test is not always accurate with normal labs.

Symptoms include but not limited to...

disabling fatigue, intermittent low-grade fevers, night sweats, arthralgias, myalgias, short-term memory loss,
confusion, irritability, depression, headaches, skin rashes, intermittent diarrhea, respiratory complaints,
photophobia and other signs and symptoms

Here is a link to Mayo Clinic

http://www.mayoclinic.com/health/lyme-disease/DS00116/DSECTION=symptoms


Treatment is usually long term Antibiotics .

Hope this helps.