http://www.sciencedaily.com/releases/2010/10/101006203003.htm
A systematic review of research into the use of nutritional supplements for the treatment of anxiety disorders has found strong evidence for the use of extracts of passionflower or kava and combinations of L-lysine and L-arginine.
Researchers writing in BioMed Central's open access Nutrition Journal pooled the results of 24 studies involving a total of more than 2000 participants, showing that some nutritional and herbal supplements can be effective, without the risk of serious side effects. The research was carried out by Shaheen Lakhan and Karen Vieira from the Global Neuroscience Initiative Foundation, a non-profit charity organization for the advancement of neurological and mental health patient welfare, education, and research, based in Los Angeles, USA. Lakhan said, "Our review and summary of the literature on herbal remedies and dietary supplements for anxiety should aid mental health practitioners in advising their patients and provide insight for future research in this field. We found mixed results -- while passionflower or kava and L-lysine and L-arginine appeared to be effective, St John's Wort and magnesium supplements were not." Of the studies included in the review, 21 were randomized controlled trials. Of these, 15 showed positive effects from either a nutritional or herbal remedy and any reported side effects were mild to moderate. According to Lakhan, "For all three of the herbal supplements we reviewed, more research needs to be done to establish the most effective dosage and to determine whether this varies between different types of anxiety or anxiety-related disorders. Herbal medicines hold an important place in the history of medicine as most of our current remedies, and the majority of those likely to be discovered in the future, will contain phytochemicals derived from plants."Research Identifies the Herbal Supplements That Are Effective in Treating Anxiety
This is interesting, but I really feel a significant reduction in my over-riding anxiety with the magnesium citrate supplement I've been taking the past 6 months or so. And I am more prone to accept a nutritional -vs- herbal supplement.
Magnesium is calming to the brain and also helps to buffer lactate, a common trigger for anxiety.
I totally believe in magnesium but it's such a fine line between too little and too much! Can't tell you how many times I crossed THAT line and ended up with the backdoor scoots! NOT FUN!
Part of it is the form of magnesium as well. Magnesium oxide burns the intestinal wall and is more likely to cause diarrhea than acidified magnesiums at the same dose.
HV, what about Magnesium Chloride for skin application?
This will help to an extent by providing the magnesium. But I still prefer magnesium malate since the malic acid it is combined with also helps with ATP formation like the magnesium itself does.
James, just so I correctly understand the dosing. You recommend 300mg 2-3 times a day. That would mean somewhere from 9 to 14 capsules a day?
http://www.vitacost.com/Source-Naturals-Magnesium-Malate-625-mg-200-Capsules/...
I am glad you asked about this because this is a very confusing issue. Unfortunately every manufacturer uses their method of measuring so there is no standardization. Some manufacturers will list the total magnesium as it is bound, and other manufacturers will list the elemental magnesium, which is more confusing. If we look at the Source Naturals label for example. The label lists 433mg of magnesium, but this elemental magnesium, and is for 6 capsules. Personally I think it would be better for manufacturers to list per capsule or tablet amounts to begin with so people do not have to divide things down to figure out their dosage. But of course they want the illusion of there is a lot more per capsule/tablet since most people will not look at the serving size to get that amount.
Anyway, back to the label. So they mention 433mg elemental magnesium but there is actually 2,933mg of magnesium malate per 6 capsules or a little over 488mg per capsule. But the description of this same product states "Source Naturals Magnesium Malate -- 625 mg - 200 Capsules". Confused yet? Most people would be.
With my recommendation I actually mean 300mg of magnesium malate, not elemental magnesium. So that would be 1 capsule three times daily, which will actually give you 133mg more than I recommend, but this is not a large enough increase to cause any problems.
I actually understand it now, thanks for the detailed explanation. If I feel better only with a double dosage of that, around 1800mg per day, is there any danger to the kidneys? No, in fact it can help the kidneys by both increasing blood flow to the kidneys and by dissolving kidney stones. The biggest issue with too much magnesium is diarrhea. And it can drop blood pressure too low in people with low blood pressure to begin with. |