I am interested to know if anyone has had this experience. I am taking natural T3 and T4 for a moderately underactive thyroid (equivalent to half a grain). I started taking this 4 weeks ago. I also take DHEA and cortisone, as well as Progesterone cream, all from the same doctor, who specialises in bio-identical hormones. I have found that my number of daily bowel movements has increased to an average of 4. I didn't really keep count before, but I know it was less than 4. Could this have something to do with the hormones I am taking?