Friends,

I was suffering HCV Gentype 3. My Age 42 yrs.

On July 2007 My Hepatologist given my Pegasys 180mcq + ribavirin 1200mg/per day 135mcq when platelet count decreases.

After six months of my therapy I found the report:

ULTRA SOUND: Portal fibrosis, Scarred Tissues & Mild splenomegaly
Had my pathology reports followed:


21.07.2009 ALT(SGPT):73 U/L
S.Bilirubin:1.0 mg/dl
Prothombine: 1.13 INR
HBsAg:Negative
Anti HCV:Reactive
HCV Quantitive: Less than detectable limits/Super Raligare SRL Mumbai
Andoscopy: Grade ii-iii Oesophaegal Varix
Moderate Degree of portal hypertensive gastropathy
Duodenal Ulcer
CBC & Blood Film: are normal except lower platelet count 108x10

After that they Made EVL
From the day the made EVL I was unable to eat very well,It was paining.
Doctor gave me some 3rd generation antibiotic
After that he made pathology test on

22/08/2009

ANA=Negative
SGOT=100 U/L
SGPT=125 U/L
Serum Total protein: 85gm/l (63-84gm/l)
Serum Albumin:38.00gm/l( - )
Anti –HBs:<3.0mIU/ml
Anti-HAV IgM:Non Reactive
Total Cholesterol:167.0mg/dl
H.D.L:51.0 mg/dl
LDL:102.0 mg/dl
Triglycerides:70.0 mg/dl
Chest P/A View:Normal

Now I am Taking medicine:
1.Leganon 75mg (Sylimarin)2x3 times daily
2.Losartan Potassium 25mg 2 times daily
3.Amino Acid 2 times (Hepa-Merz) daily.
4. Vitamin E 400 mg
5. Vitamin C 500 mg

After 1 month he advised me to made another HCV RNA test report follows:

HCV RBA: POSITIVE
HCV RNA IN IU/ml:4.7x10(7)
HCV RNA COPIES :1.9X1(9)

He PLANNED Pegylated Interferon alfa-2b (PegIntron) Maintenance Monotherapy to Reduce Esophageal Varices in Hepatitis C Patients with my Cirrhosis

My questions to you is it fatal for me to go on pegasys therapy while i am suffering Liver cirrhosis?

Thank you.