When using magnesium to treat high blood pressure, magnesium works better if taken in the absence of calcium. Magnesium works in a similar fashion as prescription calcium channel blockers (CCBs). Between the nerve ends is a gap called a synapse. When calcium enters this synapse the blood vessels constrict raising blood pressure. So CCBs work by filling the synapse to prevent calcium from entering. This relaxes the blood vessels lowering the blood pressure. Magnesium and calcium are antagonistic to each other. So higher doses of magnesium to calcium will allow the magnesium to displace the calcium out of the synapse, which again relaxes the blood vessels lowering the blood pressure. We used this principle in the hospital to lower the blood pressure of women with preeclampsia associated hypertension. IV magnesium is given to immediately drop the blood pressure.

Keep in mind that high doses of magnesium are laxative, so I generally recommend no more than 300mg of magnesium 2 times a day on an empty stomach. Taking it on an empty stomach ensures that little or no calcium will be present since the more calcium present the less effective the magnesium will be.

Magnesium malate is my first choice, followed by magnesium citrate. You should avoid any products containing magnesium oxide as this forms a caustic hydroxide (OH) when combined with water. Hydroxides are very powerful free radicals that burn tissues, and neutralize stomach acid leading to other health problems. Magnesium hydroxide is frequently used as a laxative as it chemically burns the intestinal wall leading to a fluid release and increased peristalsis. Repeatedly burning the tissues leads to an increased risk of cancer. Magnesium carbonate should also be avoided.

Also remember that as the blood pressure goes down your medication may need adjusting. So let your doctor know what you are doing, and never go off your meds cold turkey!

If the magnesium is not effective, or strong enough by itself, there are a few other options to look in to. For instance the herbs coleus forskohlii, kudzu, and cactus grandiflorus (night blooming cereus) are all excellent choices for lowering blood pressure. Cactus is a weak cardiac glycoside, so it should not be used if you are taking another cardiac glycoside like Digoxin.

Remember to drink plenty of spring water throughout the day to help flush excess salts out of the body and to keep the kidneys healthy.