I've been participating in herpes online discussions for almost as long as I've had it, over a decade. I've heard of ozone many times. The funny thing is that I always hear about it from someone who's selling it. If you understand the microbiology of the herpes virus, you'll realize that it just doesn't work that way. For a no BS explanation of why this and other "cures" don't work, check out
http://nocureforherpes.com
It's not a site selling anything, so there's no vested interest.

The best way we have today for controlling herpes is to first, have a healthy immune system. I mean by that, to simply be healthy. Eat well, get some exercise, get enough rest and take measures to reduce stress. If you have symptoms to deal with, the currently available antiviral medicines are safe and effective. If cost is a problem, generic acyclovir is quite inexpensive.

Good luck and let me know if I can help further.