- cinnamon destroys biofilms! by Tizona
14 y
19,627 3 Messages Shown
Blog: Biofilm Destruction
well this is a pleasant surprise! Was wondering if certain essential oils might have the ability to degrade biofilms.
I just randomly chose cinnamon oil, did a search for it, and found this right away.
It clearly shows that the cinnamon oil was able to degrade the biofilms successfully
http://aem.asm.org/cgi/content/full/75/21/6850
Effect of Cinnamon Oil on icaA Expression and Biofilm Formation by Staphylococcus epidermidis{triangledown}
Titik Nuryastuti,1,2 Henny C. van der Mei,1 Henk J. Busscher,1 Susi Iravati,2 Abu T. Aman,2 and Bastiaan P. Krom1*
Department of BioMedical Engineering, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands,1 Department of Microbiology, Faculty of Medicine, Gadjah Mada University, Yogyakarta, Indonesia2
Received 17 April 2009/ Accepted 6 September 2009
Staphylococcus epidermidis is notorious for its biofilm formation on medical devices, and novel approaches to prevent and kill S. epidermidis biofilms are desired. In this study, the effect of cinnamon oil on planktonic and biofilm cultures of clinical S. epidermidis isolates was evaluated. Initially, susceptibility to cinnamon oil in planktonic cultures was compared to the commonly used antimicrobial agents chlorhexidine, triclosan, and gentamicin.
The MIC of cinnamon oil, defined as the lowest concentration able to inhibit visible microbial growth, and the minimal bactericidal concentration, the lowest concentration required to kill 99.9% of the bacteria, were determined using the broth microdilution method and plating on agar. A checkerboard assay was used to evaluate the possible synergy between cinnamon oil and the other antimicrobial agents.
The effect of cinnamon oil on biofilm growth was studied in 96-well plates and with confocal laser-scanning microscopy (CLSM). Biofilm susceptibility was determined using a metabolic 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay. Real-time PCR analysis was performed to determine the effect of sub-MIC concentrations of cinnamon oil on expression of the biofilm-related gene, icaA.
Cinnamon oil showed antimicrobial activity against both planktonic and biofilm cultures of clinical S. epidermidis strains. There was only a small difference between planktonic and biofilm MICs, ranging from 0.5 to 1% and 1 to 2%, respectively. CLSM images indicated that cinnamon oil is able to detach and kill existing biofilms. Thus, cinnamon oil is an effective antimicrobial agent to combat S. epidermidis biofilms.
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Tizona
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- Re: cinnamon destroys biofilms! by Ladymix23
11 y
2,192
| Hi, i was actually suffering from staph epidermidis bacteria and it seems so hard to kill it especially when its inside the body. I havent had read many stories about forums and people with staph epidermidis infection. I want to know if there a cure on it and i hope someone has tried cinamon oil to be effective.
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Ladymix23
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- Re: cinnamon destroys biofilms! by BrightSideOfLife
10 y
2,573
When tackling a Biofilm you have to find suitable quorum sensing inhibitors in order to make what you use more effective. Without using QSI the chance of beating them is significantly reduced.
I don't think that I would risk cinnamon oil internally.
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BrightSideOfLife
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CureZone