- Diabetes Patients Suffer From Low Glutathione by Quinta_Essentia
15 y
4,813 3 Messages Shown
Blog: Boost Your Glutathione Levels
older people and people with diabetes and macular degeneration have lower GSH (glutathione) levels than younger and/or healthy people.
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T38-3TN42RD-V&_use...
Glutathione in Human Plasma: Decline in Association with Aging, Age-Related Macular Degeneration, and Diabetes
Paula S. SamiecA, B, C, Carolyn Drews-BotschB, D, Elaine W. FlaggD, Joanne C. KurtzA, B, Paul Sternberg Jr.B, *, Robyn L. ReedB and Dean P. JonesA, B
Received 12 August 1996
Abstract
Blood samples were analyzed for GSH and GSH redox state in 40 age-related macular degeneration (ARMD) patients (> 60 y), 33 non-ARMD diabetic patients (> 60 years), 27 similarly aged non-ARMD and nondiabetic individuals (> 60 years), and 19 younger individuals (< 60 years) without ARMD or diabetes. Results showed a significantly lower plasma GSH in older individuals (ARMD, diabetes, and controls) than in younger individuals (p < .01).
Total GSH (GSHt) obtained following treatment with dithiothreitol was significantly lower only in diabetic cases (p < .05) but also approached significance for ARMD cases (p = .089). Estimation of redox potential indicated that the plasma GSH pool is considerably more oxidized in all of the older groups. Analyses of whole blood GSH showed that GSH was significantly lower in diabetic cases compared to the other groups, but did not reveal any difference associated with age or ARMD. In contrast, GSSG in whole blood was significantly higher in the older groups compared to the younger controls.
The results suggest that in studies of age-related pathologies, oxidation of GSH may be a more important parameter than a decline in pool size, while in specific pathologies such as diabetes, both oxidation and a decline in pool size may be important.
Author Keywords: Glutathione; Glutathione disulfide; Redox state; Blood plasma; Human; Macular degeneration; Diabetes; Aging; Antioxidants; Free radical
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Quinta_Essentia
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- Re: Hi 5! by blubruddah
15 y
2,691
We have amedical doctor teamed up with a metaphysician in San Diego ( I cannot remmeber the name- I met him 3-6 months ago at his office..darn) who feels Glutathione is the next frontier in human development both health and Metaphysically
You seem to have gotten ahold of this persepective also?
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blubruddah
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- Re: Hi 5! by Quinta_Essentia
15 y
2,660
I have been doing a lot of research on glutathione recently as you can see and have concluded its a HUGELY overlooked nutrient in the body. the problem is that you cant just take a pill, so the supplement and/or drug companies have no incentive to promote it.
but you can raise your levels by various means. yes i believe it is very critical. my doctor just told me about alzheimers patients having big time remissions with IV glutathione.
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Quinta_Essentia
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