NITRILOSIDES
Excerpt from "Alive and Well" by Philip E Binzel Jr MD
In order to supply the necessary nitrilosides I use Amygdalin (Laetrile).
Laetrile is available in 500 mg. tablets and in vials (10cc-3 gms.) for
intravenous use. I use both forms. The dosage that I use is as follows:
The intravenous Laetrile is given three times weekly for three weeks with at
least one day between injections (Mon., Wed., Fri.). The Laetrile is not
diluted and is given by straight I.V. push over a period of one to two
minutes depending on the amount given.
The dosage for the intravenous Laetrile is:
1 st dose 1 vial (10cc-3 gms.)
2nd dose 2 vials (20cc-6 gms.)
3rd dose 2 vials (20cc-6 gms.)
4th through the 9th doses 3 vials (30cc-9 gms.)
Following this first three weeks of I.V. injections, the patient then has
one injection of 1 vial (10cc-3 gms.) once weekly for three months. If the
patient notices a considerable difference in the way he feels when the
injections are reduced to once weekly, the injections are increased to two
or three times a week for three weeks. The dose is then reduced again to
once weekly. This is repeated as often as necessary until the patient
notices no difference with the reduced dosage.
The oral Laetrile is given in a dosage of 1 gram (two 500 rag. tablets)
daily on the days on which the patients do not receive the intravenous
Laetrile. I have them take both tablets at the same time at bedtime on an
empty stomach with water. The water is important because there are some
enzymes in the fruits and vegetables and in their juices which will destroy
part of the potency of the Laetrile tablets while they are in the stomach.
Once the stomach has emptied, this is no problem.
It should be noted that I do not start my patients on their Laetrile, either
I.V. or orally, until the patients have been on their vitamins, enzymes and
diet for a period of ten days to two weeks. I find that the Laetrile seems
to have little or no effect until a sufficient quantity of other vitamins
and minerals are in the body. Zinc, for example, is the transportation
mechanism for the Laetrile. In the absence of sufficient quantities of zinc,
the Laetrile does not get into the tissues. The body will not rebuild any
tissue without sufficient quantities of Vitamin C, etc.
When I start the intravenous and oral dosages of Laetrile, I also begin to
increase the amount of Vitamin C. I have my patients increase their Vitamin
C by one gram every third day until they reach a level of at least six
grams. In some patients I use more. I find that there are some patients who
develop irritation of the stomach or diarrhea with the larger doses of
Vitamin C. I find by increasing this by one gram every third day that, if
these symptoms develop, I can reduce the Vitamin C to a level that causes no
problem. I find that most of my patients tolerate the higher doses of
Vitamin C very well.
On the days that my patients receive intravenous Laetrile I ask them not to
take their Vitamin A. There have been some studies indicating that Vitamin A
may interfere with the body's ability to metabolize intravenous Laetrile.
This has not been fully proved, but I choose to have my patients not take
their Vitamin A drops on the days on which they receive their intravenous
Laetrile. Also, I tell my patients not to take the Laetrile tablets on the
days that they receive their intravenous Laetrile. They have received
intravenously as much Laetrile as the body can handle for that period of
time. There are no ill effects from taking the tablets on those days, but
the effect of the tablets is wasted.
The level of nitrilosides in the body can be monitored. When the body
metabolizes nitrilosides, the by-product is thiocyanate. Thiocyanate levels
in the blood can be measured. I find, in general, that the patients who do
best are those in whom the thiocyanate level is between 1.2 and 2.5 Mg/DL.
This level can be raised or lowered by increasing or decreasing the dosage
of the Laetrile tablets.
I do not want to leave the impression that Laetrile is the only source of
nitrilosides. As stated in Chapter Two, there are some 1500 foods that
contain nitrilosides. These include apricot kernels, peach kernels, grape
seeds, blackberries, blueberries, strawberries, bean sprouts, lima beans,
and macadamia nuts. The advantage of using Laetrile in the cancer patient is
that Laetrile is a concentrated form of nitrilosides. It can raise the
nitriloside level in the body (and, thus, re-establish the body's second
line of defense against cancer) much more rapidly than can be done by diet
alone.