mk4 menatetrenone & nicotine

Some ideas to research. The link between Psoriasis and Parkinson's. I believe the link is Calcium Ion Channels. In our skin there is a process known as differentiation. That is when the Dermal cells change into Epidermal cells. There are Calcium Ion Channels in the skin cells that must be able to open to complete this process. It is common knowledge that Vitamin K2 will help reduce vascular calcium buildup. How does it do that? It opens Calcium Ion channels in our BONES and TEETH, allowing the calcium to enter the cells to make our teeth and bones healthy. It also opens the Calcium Ion channels in our SKIN and BRAIN. Calcium is what sends the signal in our neurons to release Neurotransmitters (Dopamine).
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The α7 nAChR subtype has one of the highest permeabilities to calcium, the activation of which can raise cytoplasmic calcium levels and trigger a series of calcium-dependent intracellular processes. Calcium ions are one of the most versatile intracellular messengers known, and impacts almost every aspect of cellular life, including excitability, exocytosis, motility, apoptosis, and transcription; this is achieved by interacting with thousands of proteins and their downstream effectors9, 10. Calcium influx through nAChRs, particularly through the α-bungarotoxin-sensitive α7-containing nAChRs, is a very efficient way to raise cytoplasmic calcium levels. Here we will present a brief summary of the calcium signals initiated by the activation of neuronal nAChRs, and its possible physiological relevance.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002362/

Vitamin K2 also affects these receptors by opening the calcium ion channels. It is well known it does this in your In your teeth and bones, but it also does it in your BRAIN AND SKIN. Your cells need the MK4 form Menatetrenone. MK7 can be converted, but it has to be converted for your cells to use it.

People with Psoriasis are at greater risk of getting Parkinsons or Parkinsonism. It may be related.
https://duckduckgo.com/?q=parkinsons+psoriasis&t=vivaldi&ia=web

I believe people with Parkinsons will benefit from Vitamin K2 MK4 Menatetrenone along with the nicotine. They both are needed. Nicotine is a Phytonutrient found in all Nightshade vegetables. It is not addictive. Calcium Ion Channels need to be opened, which is what sends the signal for Neurotransmitter release.
https://www.brainfacts.org/Brain-Anatomy-and-Function/Cells-and-Circuits/2018/Calcium-Sends-the-Signal-110218

Take Menatetrenone 5 mg twice daily, If you have Psoriasis. It got rid of mine. If you have Parkinsons, or both, take the Nicotine as Dr. Ardis said, and try adding the MK4 Menatetrenone.
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NICOTINE can help too https://rumble.com/v2a1qza-nicotine-understanding-the-weapon-and-the-target.html
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Calcium channel blocker-induced parkinsonism: clinical features and comparisons with Parkinson's disease
https://pubmed.ncbi.nlm.nih.gov/18591113/
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