Treatment of human pulmonary paragonimiasis with triclabendazole:
Triclabendazole can be recommended as an alternative drug of choice for the treatment of pulmonary paragonimiasis; it is as effective as praziquantel in clearing infections and better tolerated.
[Fascioliasis (treatment)]1—Triclabendazole is used as a primary agent in the treatment of fascioliasis caused by Fasciola hepatica (sheep liver fluke) and Fasciola gigantica (giant liver fluke)
Not commercially available in the U.S.
†Not commercially available in Canada
Paragonimiasis (treatment)]1—Triclabendazole is used as an alternative agent in the treatment of paragonimiasis caused by Paragonimus westermani (lung fluke)
Triclabendazole has shown no activity against nematodes. It differs from the other benzimidazole anthelmintics (e.g., albendazole, mebendazole) currently used in humans since these compounds have selective activity against nematodes and have no significant activity against flukes and other trematode helminths