altitude sickness

I'm going on vacation soon and I've never been at such a high altitude. I've been reading up on altitude sickness and it is concerning me. As far as prevention goes, people have recommended getting a prescription from the doctor for something called DIAMOX. I've tried to research it but I'm still unclear on exactly what it is supposed to do.

In any case, does anybody have some kind of alternative/holistic approach to prevent altitude sickness?

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