Biomimetic Nanomedicine

Nanomedicine Development Goals To improve efficacy, accuracy, safety or compliance in the diagnosis and treatment of disease by utilizing the unique properties of engineered nanomaterials.

Only a small number of proposed nanomedicines are currently being used clinically in patients or in clinical trials. Most nanomedicines are typically “foreign bodies” and are subject to biological barriers such as opsonization, immune clearance, and negotiation with the vasculature. Since synthetic systems are still not sufficient to fully reproduce the complexity of cellular systems, biomimetic nanomedicines have recently been developed through top-down engineering of biological membranes into delivery systems that retain some of the key functions of membrane proteins of the cells of origin.

Schematic representation of different approaches to the design of bioinspired and biomimetic nanomedicine based on cellular or synthetic systems. Without further mimicking the surface of artificial nanomaterials,  nanovesicles derived from cell membranes can also be used directly as biomimetic nanomedicine.

These types of biomimetic nanovectors, also known as nanoghosts, are used for drug and gene targeting studies. Interesting applications of biomimetic and bio-inspired nanomedicine are envisaged to treat numerous diseases associated with different indications through unique structural and functional designs, different routes of administration, and learning from nature to improve our lives. You should know more about nanomedicines and nanoparticles.

Involvement in Healthcare 

Healthcare as a basic human right has developed innovative technologies. Technological advances have greatly contributed to the delivery of quality, timely, acceptable and affordable healthcare.

Advances in nanoscience have led to the emergence of a new generation of nanostructures. Nanotechnology is already expanding the medical tools, knowledge and therapies currently available to clinicians. Nanomedicine, the application of nanotechnology in medicine, is based on the natural scale of biological phenomena to develop precise solutions for the prevention, diagnosis and treatment of diseases. 

Here are some examples of recent advances in this area: 

• Nanotechnology researchers are working on different therapies where a nanoparticle can encapsulate drugs or otherwise help deliver drugs directly to cancer cells, minimizing the risk of harm to healthy ones' Tissue.

• This has the potential to change the way doctors treat cancer and drastically reduce the toxic effects of chemotherapy. 

• Nanomedicine researchers are exploring ways nanotechnology can improve vaccines, including delivering vaccines without the use of needles. Researchers are also working to create a universal vaccine scaffold for the annual influenza vaccination that covers more strains and requires fewer resources to develop each year.

• Nanotechnology is being studied for both the diagnosis and treatment of atherosclerosis, or the build-up of plaque in the arteries. In one technique, the researchers created a nanoparticle that mimics the body's "good" cholesterol, known as HDL (high-density lipoprotein). , which helps reduce plaque. 

• Nanotechnology is already leading to dramatic improvements in healthcare. Scientists are using nanoparticles to target tumors, in drug delivery systems, and to improve medical imaging. About nanoparticle-based treatments are multifunctional; they can find tumors and carry drugs to treat them.

• Nanotechnology is also being used to reduce costs and increase the speed of DNA sequencing and provide a scaffold for tissue regeneration or wound treatment.

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