Since enemas are not part of any Herbdoc Richard Schulze protocol I know of, perhaps you've adapted enemas as part of your own protocol. Either way, you should do them when you feel your lower colon is in need help getting flushed. This could be prior to starting any protocol, cleanse, fast, Schulze 30- day cleanse or otherwise, during or after. As for frequency, during the cleanse, it depends somewhat whether or not your bowels are moving on their own. If they are, an enema once a week helps rinse out whatever the fasting and cleansing has sent to your bowel, if not, perhaps one every two or three days will help you maintain pseudo regularity so to speak.