Re: Metformin slows growth of tumors lacking p53 by Aharleygyrl ..... News Forum
Date: 8/16/2007 12:47:31 PM ( 17 y ago)
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URL: https://www.curezone.org/forums/fm.asp?i=942987
And, Dr. Dean Ward has information indicating that Metformin is the most effective life extension drug there is. I was asked a question about dosage for someone's father who is on Metformin, so I answered it. I post on health and I take Metformin (so does my Mother). Owning stock would not influence me but, I don't buy from American companies because they way overcharge.
Incidentally, The Life Extension Foundation is where this article came from.
You said:
"I think we could argue this point indefinitely. If you vouch for them then that is good enough for me - you strike me as honest and sincere, so I accept that they are good folks who use a lot of natural things and also take approved meds."
Suffice it to say, you don't like Metformin and I do. To me, it is health news. You are free to post in opposition to my article, but I could do without the owning stock type comments.
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Because of the depletion of B12, supplementation is recommended.
I will restate as well:
Many helpful side benefits
Metformin's multiple effects benefit individuals with a propensity to develop diabetes, cardiovascular problems, endocrine problems, retinopathies, nephropathies, cancer or decreased immunity, infections and weigh gain.(1-5,8)
As with diabetes, metformin has been shown to cause a reduction in appetite, weight, and the body's total fat content. In associated heart disease conditions, there is plaque build-up that lines the arteries. This build-up of plaque can lead to atherosclerosis.(8) Metformin reduces or lowers the chances of developing atherosclerosis and reduces the rate of pro-aging cross linkages of collagen, which plays a role in the scar tissue build-up that cccurs during wound healing.(4)
Metformin has been shown to reduce the amount of supplemental insulin needed by type II diabetics who become insulin-dependent. They are able to take a lower insulin dose in conjunction with metformin without the risk of becoming hypoglycemic. For 40 years metformin has been used to control blood glucose levels in patients with type II diabetes. Physicians are recommending it to patients who are predisposed to diabetes for the prevention of developing the disease.(8)
With the cluster of cardiovascular problems associated with hyperinsulinemia, metformin has proven effective in lowering total cholesterol, low density lipids, free fatty acids, tissue plasminogen activator antigen and insulin levels when patients present with symptoms of hypertension dyslipidemia, visceral obesity or hyperglycemia. Metformin prevents the acceleration of atherosclerosis and reduces the rate of pro-aging cross linking of collagen. The microvascular complications of hyperinsulinemia are improved by metformin due to the arterial clearance in small blood vessels of the eyes, kidneys and nerves.
There are other positive effects associated with metformin: decreased tumor growth and improved cellular immunity in individuals who are prone to chronic infections associated high blood sugar levels. In non diabetics, metformin reduced low density lipid, total cholesterol, free fatty acids, tissue plasminogen activator antigen, blood pressure and fasting triglyceride levels.(1-5,8)
Women suffering from polycystic ovary syndrome have been treated with metformin. Benefits include: lipid lowering effects, reduction in systolic blood pressure, hyperinsulinemia and insulin resistance syndrome. Metformin has also been shown to aid in normal menstrual regulation and pregnancy.(10,11)
In conclusion, the scientific research points to metformin's multiple uses, with few drawbacks. Accordingly, the drug's numerous side benefits associated with the treatment and prevention of diabetes, as well as other disorders, appear to outweigh its limited side effects.
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