Re: Halide Imbalance Syndrome prevention by digitalman ..... Iodine Supplementation Support by VWT Team
Date: 1/25/2007 3:22:03 PM ( 17 y ago)
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URL: https://www.curezone.org/forums/fm.asp?i=819987
I actually have a degree in chemistry - I love when it comes in handy (since work is not that challenging).
It makes sense that we probably need a specific ratio of iodine/iodide for optimal performance.
But the fact that I2 (neutral form) is a solid at room temperature and only slightly soluble in water, it would seem to make I2 usage by the body very scarce. In ionic form it may be readily absorbable, making me think that all the Iodine forms must either be absorbed has halogenated organic compounds (like the oil) or in ionic forms like various salts.
Perhaps then the body will convert those forms into neutral Iodine if needed.
I took an excerpt from the website describing the mechanism of action in the thyroid, where it seems that H2O2 (Hydrogen-Peroxid) is used to convert Iodine forms for usability.
Mike
From
http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/iod_0146.shtml
"Iodine in the form of Iodide is preferentially taken up by the thyroid gland. Iodide is accumulated in the thyroid by means of an active Iodide transport mechanism which is catalyzed by a sodium/iodide symporter, which mediates the sodium/potassium ATPase-dependent coupling of inward iodide and sodium fluxes. The thyroid gland is not the only organ capable of iodide uptake. However, the thyroid is the only organ known to organify iodide. Iodide is released by the thyroid cells into the colloid follicle phase, and there it is oxidized by hydrogen peroxide formed from the thyroid peroxidase system. Iodine reacts with tyrosine residues in thyroglobulin to form thyroxine (T4) and triiodothyronine (T3). The formation of T4 and T3 takes place post-translationally. The iodinated thyroglobulin is absorbed back into the thyroid cells where proteolytic enzymes break it down. The thyroid hormones T4 and T3 are released into the circulation and distributed to the various tissues of the body.
Potassium iodide may be used following radiation exposure from a nuclear reactor accident. Pharmacological doses of iodide block uptake by the thyroid of radioactive isotopes, particularly 131I, thus minimizing the risk of radiation-induced thyroid cancer."
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