Re: Candida biofilms and antifungal resistance. by dvjorge ..... Candida & Dysbiosis Forum
Date: 6/25/2014 8:27:50 PM ( 11 y ago)
Hits: 4,591
URL: https://www.curezone.org/forums/fm.asp?i=2183698
The enzyme can not be used. Maybe combined with one or more antifungals ??
Found it:
Abstract
Candida albicans is the most common human fungal pathogen. Many organisms, including C. albicans, secrete glucanases under different environmental conditions. Here, we report a novel role for beta-1, 3- glucanase in inducing Candida albicans to form filaments at 22°C and enhancing filamentation at 37°C in nutrient-rich medium. Quorum sensing, the efg1-signaling and cek1 MAP kinase pathways are involved in this process. Our data suggest that the natural antifungal agent beta–glucanase may support morphologic transformation of Candida albicans at a wide range of ambient temperatures.
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