Date:   7/6/2012 10:16:53 PM ( 12 y ago)
Hits:   19,529
URL:   https://www.curezone.org/forums/fm.asp?i=1960577

Candida Albicans yeast as a mobile commensal fungus tends to gravitate towards regions of the body where it has a nutrient-rich supply of resources and also where it is able to exert a certain degree of host-control. The upper region of the esophagus adjacent to the thyroid satisfies both of these constraints. Entrenched there Candida Albicans has first choice of any ingested materials before they descend into the somewhat harsh acidic environment of the stomach. Also, possibly via acetaldehyde-mediated suppression of thyroid response to its activating hormone TSH, yeast colonization in this region can down-regulate the response of the immune system to its presence.

See acetaldehyde+GPCRs //www.curezone.org/forums/fm.asp?i=1955511

and, Schaefer et al. http://www.fasebj.org/content/25/1/29.full

If this supposition is true, then there should be other biomarkers of its colonization in this region.

Sore throats are a common occurrence with millions of emergency department instances of throat-related cases in the United States every year. The most common cause is viral infection. But what makes the throat and adjacent tonsils so vulnerable to infection?

If acetaldehyde in the gut can disrupt the tight junctions proteins in the intestinal wall leading to "leaky gut", then yeast-released acetaldehyde in the esophagus could similarly alter the epithelial permeability in this sensitive region leading to "leaky throat" with inflammation, soreness, and susceptibility to infection (classic symptoms of sore throat) the result.

See acetaldehyde+leaky gut //www.curezone.org/forums/fm.asp?i=1956265

A connection between the integrity of tight junction proteins and the common condition of acid reflux has also been established:

See Asaoka et al. http://www.ncbi.nlm.nih.gov/pubmed/16143882

A sneeze is an autonomic reflex used by the body as a first line of defense in an attempt to physically clear invading material including viral activity from the respiratory passages. Budding activity of yeast and release of acetaldehyde will increase after the consumption of certain foods. If there is yeast-induced acetaldehyde irritation in the esophageal tissues potentially leading to loss of tight junction integrity, is acid reflux a similar autonomic response to attempt to eliminate the pathogenic behavior by exposing whatever is causing the damage to the acidic environment of the stomach?

Recent studies have demonstrated a role for the tonsils in the production of immune system T-cells:

See McClory et al http://www.jci.org/articles/view/46125

elevating the utility of these often-infected and often-removed lymph nodes at the top of the throat from just passive blocking of inhaled or ingested pathogens to an active participation in the systemic biochemistry of the immune system.

Aldehyde fuchsin intensely stains tonsil tissue:

See Sunami-Kataoka et al. http://www.ncbi.nlm.nih.gov/pubmed/11838713

indicating that these endothelial cells would be exquisitely sensitive to attack by acetaldehyde molecules released by budding yeast metabolism.

This model of yeast-produced, acetaldehyde-mediated disruption of both the tight junction proteins in the lining of the esophagus and of the epithelial cells of the tonsils may explain why steeped garlic tea, an antifungal (i.e. anti-yeast), is a frequently recommended home remedy for sore throats. Furthermore, it elucidates why a liquid acetaldehyde scavenger such as Wondro or emulsified NAC is more efficacious than an encapsulated one (something that bypasses this vulnerable region completely on its way to the stomach).
 

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