Re: DEC PET: 5.8 x 2 x 4.4 cm ||| MAY PET: 5.2 x 2.3 x 5.3 cm by Hveragerthi ..... The Truth in Medicine
Date: 12/9/2011 6:05:00 AM ( 13 y ago)
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L x W x H is not a perfect measuring tool, as the tumor is probably not a perfect rectangular prism, but unless it has some very strange shape, I think that this is good enough. How do oncologists typically measure the volume of a tumor? Do they go by volume?
It will not be a true volume since it is not even, but yes it is a rough volume based on the length, width and height.
If I calculate the tumor as an ellipsoid, I still get almost the same difference in volume: ~22% shrinkage. Is my ~22% figure about right? What do you make of the fact that it grew in one direction and got smaller in the other two? Her tumor is, in fact, smaller, correct?
I am not the greatest at math, but it sure sounds to me like it has shrunk. And I still believe that much of the remaining mass is scar tissue, not malignant cells.
The RECIST method yields about about a 17% shrinkage, but also a good bit more if I believe the "Note that actually tumors have three dimensions so a partial response in either system actually means more than a 50% reduction in tumor volume" statement.
--> http://cancerguide.org/endpoints.html
EDIT: The bone pain greatly diminishes after a bit of walking and moving and her bone pain is worst after waking up or sitting for a while. I'm assuming that cancer does not react to exercise in this kind of way.
Correct. The reduction in pain is most likely due to increasing the circulation.
When she takes more oxycodone, like 2 x 20mg every 3 hours, her pain also greatly diminishes, so it could also partly be withdrawal from taking half as many pills as you suggested earlier.
Yes, this will contribute as well.
EDIT 2: While my mom has definitely been eating healthier than she has ever been in her whole life, she is still not eating as healthy as I'd like her to. How important is her diet?
I would not put it at the top of the list, but it does play a role as certain foods can adversely affect the immune system or contains hormones (meats and dairy) that can definitely contribute to cancer growth.
She typically mixes whole grains and refined grains, eats at least two fruits a day (mostly apples, oranges, and raspberries), some vegetables (pickled cabbage, tomatoes and cucumbers, leaves of different kinds) but not an entire 8 servings per day, organic kefir, some meat and sweets. She has reduced her meat consumption, but eats these organic, uncured, grass-fed hot dogs (no nitrites, but they do have celery powder which may be the same thing) whenever I can buy them. She especially loves sugar snap peas and I pick them up in bulk when I'm in Manhattan. I will pick up some organic, unsweetened soy milk in a few days for her, as the one she's been sometimes drinking is sweetened with 6g of sugar which she says is to sweet for her. How does soy milk compare to soybeans, something that I know you recommended earlier?
It will be lower in phytoestrogens, but there will still be some benefits from the remaining phytoestrogens.
What should we be adding and subtracting from her diet?
Just keep meats and non-cultured dairy to a minimum as well as sugars.
There are numerous indicators that suggest she's improving (tumor decreased in size, milk stopped coming out, pus stopped coming out because the wounds have closed, SUV numbers have decreased by half everywhere except for the new ones around her ribs and throat, skin thickening reduced in half, lymph nodes decreased in size, pain has greatly improved), but we'd like to expedite the process, plus there are some worrying indicators, which may or may not be related to cancer ("findings compatible with bone metastasis," the fluid buildup around her heart and chest, increased bone pain).
The only thing I saw of concern was the still pretty high SUV of the one mass. The pleural effusion is likely just from the inflammation and i think the bone pain is unrelated..
EDIT 3: Can cancer spread from its initial tumor area if the tumor has been gradually shrinking, like in my mom's case?
It is possible, but the primary tumor suppresses growth of the secondary tumors and the secondary tumors would be significantly more prone to destruction by the ozone. Therefore, I seriously doubt there are any metastasized cells.
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