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COENUROSIS: Tapeworm Larva Cysts ~ Soft Tissue, Muscles, CNS, & Eyes by ICU ..... Parasites: Skin Support

Date:   11/10/2010 7:58:48 PM ( 14 y ago)
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URL:   https://www.curezone.org/forums/fm.asp?i=1721955

  Coenurosis ~ Tapeworm Larva Cysts ~
Soft Tissue, Muscles, Eyes, & CNS
 
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Coenurus Taenia serialis
 
Coenurosis is a parasitic infection of tapeworm larva cysts in soft tissue, muscles, eyes, or central nervous system (CNS).  It results when a person accidentally ingests eggs of the dog tapeworm Taenia multiceps, T. serialis, T. brauni, or T. glomerata.
 
There are many tapeworm species in the genus Taenia, but these four are responsible for the human disease of Coenurosis.

It's important to distinguish the significant difference between a human Tapeworm Infection & Coenurosis.

Humans are definitive hosts for many types of tapeworms, the most common being T. saginata & T. solium (beef & pork tapeworms).  These develop into reproductive adult worms in the intestines of humans.  A person infected with these species has a Tapeworm Infection.

In contrast, the four species that cause human Coenurosis can only grow into mature reproductive worms in their definitive canid hosts, such as dogs, wolves, foxes, & coyotes.

Humans who ingest eggs from any of these four Taenia species are intermediate hosts, where the eggs can mature into larva but not into adult worms.

When a person ingests these eggs, they develop into tapeworm larva that group within cysts known as coenuri.  These cysts can be in muscles, subcutaneous tissue, eyes, & the CNS.  A person infected with these encysted larva has a Coenurus Infection.
Coenurus Taenia multiceps cyst
Life Cycle:
Eggs & gravid proglottids are shed in feces into the environment by infected definitive hosts (canids).

Many animals serve as intermediate hosts, including rodents, rabbits, cattle, sheep, goats, & humans by ingesting the eggs.

Once ingested, the eggs hatch in the intestines, releasing oncospheres.  These circulate in the blood & lodge in body organs, subcutaneous tissue, skeletal muscles, eyes, CNS, or spinal chord.

After about three months, the oncospheres develop into cystic-like larva balls called coenuri.

The cycle perpetuates when a canid (definitive host) ingests the tissue of an infected intermediate host. 

When this happens, the maturing larva reside in the small intestine of the definitive host, mature into adult worms, & begin producing eggs.  These pass through feces into the environment once again.

Clinical Presentation:
The clinical course of Coenurosis is usually insidious & chronic.  Symptoms may take several years to develop & depend on the location of the larva or coenuri.

The species T. brauni, T. serialis, & T. glomerulus cause subcutaneous tissue & muscle infection.  When coenuri develop in muscles, a painful nodule often results, & a visceral larval migrans syndrome may develop.

Subcutaneous coenuri produce a nodule similar to those in muscle tissue, but it tends to be painless.  The nodules are usually smaller than 6 centimeters in diameter.  They are commonly located in the trunk but can also be found in the neck, head, or limbs. 

Systemic allergic symptoms have also been reported in cases of Coenurosis of the breast. 

In the eye, the coenuri take on either an intraocular or orbital form in the subconjunctival space, eyelids, or extrinsic muscles.  The symptoms are blurred vision or diplopia. 

If coenuri enter the brain, meningeal symptoms may include headache, transient hemiparesis, & epileptiform seizures, increased intracranial pressure, & loss of consciousness.  The full-blown syndrome is a space-occupying lesion.

 
Coenurus Taenia Multiceps
 
Symptoms:
In humans, Conenurosis causes a variety of symptoms, depending on where the cyst occurs.

The tapeworm larva group together to form fluid-filled cysts in various body tissues.  A cysts starts out small, but as the larva grow, it can reach the size of an egg.

The cysts of T. multiceps are usually between 2 and 6 cm in diameter & can contain a few to over a hundred worm larva.  They encyst in subcutaneous tissue, CNS, muscles, or eyes.

T serialis & T. glomerata cysts present in the CNS, muscles, or soft tissue. 

T. brauni cysts occupy these same areas but occur in the eye more frequently than the other three species.

When a cyst occurs in the brain, symptoms are headaches, seizures, vomiting, paralysis affecting one side of the body (hemiplegia), paralysis involving one limb (monoplegia), & loss of ability to coordinate muscles & muscle movements.  These symptoms are due to buildup of inter-cranial pressure from the growing cyst or from the cyst pressing on other parts of the brain.

If a cyst occurs in the spinal chord, it can cause severe pain, inflammation, & loss of feeling in some nerves.

A cyst in the eye causes decreased vision & headaches.

In muscular & subcutaneous tissue, the cyst can cause disfiguring nodules that protrude out of the body.  These nodules can be painful & cause loss of muscle function.

Diagnostic Methods:
Because this disease is uncommon, accurate diagnostic techniques have not been developed.

CT scans and MRIs are used to detect fluid-filled cysts in all areas of the body.  Serological & microscopic tests can confirm Taenia larva when a portion of a cyst is surgically removed for examination & biopsy.

Because of a lack of specific diagnostic techniques, Coenurosis can be misdiagnosed as Cysticercosis, Neurocysticercosis, or Echinococcos, which are other parasitic diseases of soft tissue, muscles, eyes, organs, or CNS.

If a person with symptoms lives in an area with poor sanitation, high wild dog population, or known endemic tapeworm, the chance of having Coenurosis is high.

This disease occurs more often in children because they spend more time outside than adults & are more likely to come into contact with canid feces.

Also at risk of infection are persons who reside, camp, garden, landscape, work, or hike in rural, wooded, or wildlife areas.

Taenia multiceps
Treatment:
The most common treatment for Coenurosis is surgical removal of the cysts, but this isn't always possible.   Surgery is more difficult for cysts in the CNS than in the muscles or subcutaneous tissue.
 
Anthelmintic Drugs:

Praziquantel (Biltricide):  Causes cell membranes of worms to become permeable.  In this way, the worm loses intracellular calcium.  This in turn causes the worm to become paralyzed.

Niclosamide (Niclocide):  By causing the death of cells in the head & adjoining segments, this drug causes the worm to let go of whatever it's attached to in the human body.  The worm is then excreted in the feces.

Albendazole (Albenza):  Causes the worm to produce less ATP, eventually leading to its death.
 
Glucocorticoids:  Dexamethasone (Decadron) is used for inflammatory symptoms of the disease for patients with elevated intracranial pressure.
 
Prevalence/Endemic Regions:
Coenurosis is uncommon in the Western Hemisphere, with the majority of cases (65%) occurring in Europe & Africa.  Distribution of the different species that cause Coenurosis are:
 
Taenia multiceps:  France, Africa, England, Brazil, & the United States.
Taenia serialis:  Canada, United States, Europe, & Africa 
Taenia brauni:  North Africa, Rwanda, & Democratic Republic of Congo.
Taenia glomerata:  Nigeria & Democratic Republic of Congo.
 
T. multiceps has been reported in regions all over the world (both human & animal infections) & is the most common Conenurosis-causing species.
 
Coenurosis occurs even in developed countries.  Some of the most recent reported cases were in France, Italy, Israel, Canada, & the United States.
 
Experts estimate under-reporting of this disease, especially in impoverished & developing countries.  The global prevalence may be much higher than present data suggest.
 
 
Coenurus Taenia multiceps cyst
Reported Cases:
Within the last 25 years, human cases were recorded in Uganda, Kenya, Ghana, South Africa, Rwanda, Nigeria, Italy, Israel, Mexico, Canada, & the United States.  Animal cases have been found in many other countries as well.
 
In 1983, a 4-year old girl in the USA was admitted to the hospital with progressive, generalized muscle weakness, inability to walk, rash, abdominal pain, & deteriorating neurological ability.  When the doctors did a CT scan, they saw fluid-filled lumps in her brain & decided to operate.  While operating, coenuri were found & the patient was immediately given chemotherapy with praziquantel.  However, the disease had seriously damaged the CNS, & the child didn't survive.
 
Another North American case occurred in 1994 in Los Angeles, CA.  A 39-year old man had an enlarged mass on his back.  When doctors operated, a large intramuscular capsule was found.  The surgery was terminated, & a fine needle aspiration test revealed muscular Coenurosis.  The man was treated with praziquantel.  The drug successfully killed the larva, & reinfection didn't occur.
 
Another case took place in Israel in 2006.  A 4-year old girl had T. multiceps in subcutaneous tissue.  She received antiparasitic drugs & made a full recovery. 
 
In these cases, the infected individuals had been exposed to wild dogs in regions where canid tapeworm is endemic.  They probably ingested the parasite accidentally through contact with contaminated food or water.
 
Prevention:
This disease has no vaccination.  Communities can ensure their water supply remains sanitary & free of dog feces.  They can control wild dog populations & vaccinate dogs for tapeworm infections. 
 
Individuals should wash all fruits & vegetables, cook all meats thoroughly before eating, & ensure their dogs aren't infected with tapeworms & other parasites.
 
References:
http://www.stanford.edu/group/parasites/ParaSites2005/Coenurosis/coenurus.htm
 
Coenurus Tapeworm Drug Treatment Protocol ~ Niclosamide, Praziquantel, & Albendazole:  http://curezone.com/forums/fm.asp?i=1602094#i
 
Topical Treatments ~ Parasites In Skin, Soft Tissue, & Scalp:  http://curezone.com/forums/fm.asp?i=1628614#i 
 
Cheers ~~ ICU
 
stock photo : Stretching Foreign White cat

My Curezone Posts:  http://curezone.com/forums/s.asp ?f=762&c=0&ob=d&m=ICU

Parasite Drug Protocols:  Roundworms, Tapeworms, Flukes, Strongyloides, Morgellons, & Protozoa:  http://curezone.com/forums/fm.asp?i=1574645#i


 

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