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Re: Too much of a good thing nearly killed Gary Null by chrisb1 ..... News Forum

Date:   4/29/2010 4:09:40 PM ( 15 y ago)
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URL:   https://www.curezone.org/forums/fm.asp?i=1614469

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I agree with parazapper.

It also depends on which Vitamin D was used and for what period of time.
Vitamin D toxicity is highly unlikely unless consuming at least 40,000ius or more per day over several months.

"Animal data indicates signs of toxicity can occur with ingestion of 0.5 mg/kg (20,000 IU/kg ), while the oral LD50 (the dose it takes to kill half the animals) for cholecalciferol in dogs is about 88 mg/kg, or 3,520,000 IU/kg. An Overview of Cholecalciferol Toxicosis. The American Board of Veterinary Toxicology (ABVT). This would be equivalent to a 110-pound adult taking 176,000,000 IU or 440,000 of the 400 unit cholecalciferol capsules.
Professor Vieth reports human toxicity probably begins to occur after chronic daily consumption of approximately 40,000 IU/day (100 of the 400 IU capsules)".....................
http://www.ncbi.nlm.nih.gov/pubmed/10232622


And........

Cholecalciferol (Vitamin D3), Not Ergocalciferol (Vitamin D2), Is Safe...........................

Although there are documented cases of pharmacological overdoses from ergocalciferol, the only documented case of pharmacological—not industrial—toxicity from cholecalciferol we could find in the literature was intoxication from an over-the-counter supplement called Prolongevity. Koutkia P, Chen TC, Holick MF. Vitamin D intoxication associated with an over-the-counter supplement. N Engl J Med. 2001 Jul 5;345(1):66–7. On closer inspection, it seemed more like an industrial accident but it was interesting because it gave us some idea of the safety of cholecalciferol. The capsules consumed contained up to 430 times the amount of cholecalciferol contained on the label (2,000 IU). The man had been taking between 156,000–2,604,000 IU of cholecalciferol a day (equivalent to between 390–6,500 of the 400 unit capsules) for two years. He recovered uneventfully after proper diagnosis, treatment with steroids, and sunscreen.

It is true that a few people may have problems with high calcium due to undiagnosed vitamin D hypersensitivity syndromes such as primary hyperparathyroidism, granulomatous disease, or occult cancers, but a blood calcium level, PTH, 25(OH)D, and calcitriol level should help clarify the cause of the hypersensitivity. Although D can be toxic in excess, the same can be said for water.

Chrisb1.
 

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