Date:   3/31/2009 2:44:06 PM ( 15 y ago)
Hits:   12,683
URL:   https://www.curezone.org/forums/fm.asp?i=1386674

Hi John,

The below article talks about a treatment option using accutane and dapsone together. You may want to contact the doctors that did the study. Hope this helps. 7621


Successful treatment of perifolliculitis capitis abscedens et suffodiens with combined isotretinoin and dapsone
Sven Bolz, Uta Jappe, Wolfgang Hartschuh
Correspondence to Dr. S. Bolz Universitäts-Hautklinik Heidelberg Voßstr. 2 D-69115 Heidelberg Tel.: +49-62 21-56 70 11 Fax: +49-62 21-56 46 22 E-mail: sven.bolz@med.uni-heidelberg.de



Perifolliculitis capitis abscedens et suffodiens (PCAS) is a rare scalp disease of unknown etiology which is hard to treat.It is often accompanied by scarring alopecia, Acne conglobata, and recurrent fluctuant abscesses. PCAS belongs to the family of Acne inversa (hidradenitis suppurativa). A 19-year-old man presented with PCAS for 2 years; multiple systemic Antibiotic therapies and surgical approaches had shown no effect. Monotherapy with isotretinoin 80 mg daily for 4 weeks had not been successful. Combination therapy with dapsone 100 mg and isotretinoin 80 mg daily produced significant improvement. During 4 weeks of treatment significant clearing was achieved.Dapsone was reduced to 50 mg daily after 6 months, while isotretinoin was discontinued gradu-ally.Now the patient is on dapsone 50 mg every other day and has remained free of recurrences for 6 months.


 

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