Date:   9/19/2008 10:17:49 PM ( 16 y ago)
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URL:   https://www.curezone.org/forums/fm.asp?i=1261348

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Accutane may result in hypervitaminosis A, which causes hair loss.

But here's why hair loss happens - Hypervitaminosis A causes low levels of biotinidase. Biotinidase is an enzyme that regulates biotin. Biotinidase deficiency means biotin deficiency.

An old laboratory study showed that rats fed with low biotin levels lost all their hair, but when once taking high doses of biotin their hair restored.

According to
http://www.emedicine.com/PED/topic239.htm
: "Although they may be severe, the rash and alopecia typically respond rapidly to biotin administration over days to months."

So I suggest any accutane victim to take biotin suplementation. If possible more than once a day (if possible timed-release) because it's not stored in the body since it's water soluble and goes away with urine and sweat. Also take a good B Complex as biotin interact with these vitamins. Up to 5mg (=5.000 mcg) daily should be OK, since there are pills with that much biotin content. Commom vitamin supplements only offer a very small amount of biotin, which wouldn't be enough.


 

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