Date:   5/19/2008 11:37:55 PM ( 16 y ago)
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URL:   https://www.curezone.org/forums/fm.asp?i=1176409

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It is a fallacy to assume that we can treat Depression or any other mood disorder by the supplementation of single remedies or a number of single remedies. This is following the disastrous medical model based on single drug therapy, that assumes that by ingesting "single" drugs, we can can "cure" serotonin deficiency.

Natural therapists tend to imitate psychiatrists and doctors by assuming that since drugs are poisonous, natural single remedies may be the alternative. People should realize for the body to produce one particular neurotransmitter such as serotonin a whole orchestra of nutrients is required, just not some single co-enzymes like vitamin B6 or an amino acid, tryptophan. The necessary ingredients and precursors of serotonin runs into the hundreds, still a mystery to most nutritional biochemists.

Then we should add each person's individuality of biochemistry, where one set of food sources may be poison to another person. One man's meat is another man's poison.

I have explained this in:

Hit or Miss Supplements for Depression

http://www.hypoglycemia.asn.au/articles/hit_miss_supplements.html


where I am emphasizing the totality of nutrition, rather than concentrate on individual nutrients or remedies as is the habit of doctors. Human biochemistry is far too complex for this.

The cardinal rule in nutritional therapy is that nutrients work in co-operation with other nutrients. For instance, vitamin B6 is essential in the conversion of tryptophan to serotonin, but this vitamin is also dependent on the presence of zinc. Vitamin B6 (pyridoxine) needs to be converted to an active form called pyridoxal-5-phosphate (P5P) (or PLP), by a zinc containing enzymes - pyridoxine kinase. And tryptophan will not be available if there is a Vitamin B3 (niacin) deficiency. Furthermore, a riboflavin deficiency may also cause a B6 deficiency, as this is one of the necessary co-enzymes to PLP formation. Human biochemistry cannot operate in the absence of biological energy (ATP) and so on. AND zinc absorption is in turn dependent on the production of picolinic acid. Thus there is a massive interdependency of nutrients that may prevents us from playing GOD.

Please search our web site for "vitamin B6, zinc".

In one way human biochemistry is too complex to experiment wit single nutrients, on the other hand we can simplify this by looking at total nutrition and going back to some basics in nutritional science.


 

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