Re: Off Topic – Bone Health & Density Study by #38782 ..... Ask Microbe Detectives
Date: 4/6/2008 4:48:46 PM ( 16 y ago)
Hits: 3,425
URL: https://www.curezone.org/forums/fm.asp?i=1148629
Thanks for the info. Does this have to be a supplement? Is it possible to take in Potassium Citrate naturally...
Since we´re on this (off!-)topic - here´s some very interesting info I read on the "News Forum" a short while back re Bone Health and Density. Since I´m not for supplementing and prefer going the natural "route", it´s interesting that they mention fermented Soyabean as a source for the Vit. K2. Would be nice to know if there are other (natural) sources for Vit. K2.
Best regards!
NATTO: Vitamin K2 supplementation shown to improve hip bone geometry and bone strength indices in postmenopausal women in the Journal Osteoporosis International
NattoPharma, Norway recently announced new findings for the dietary
supplement MenaQ7 with significant potential benefits for bone health
in postmenopausal women. Vitamin K2 supplementation was shown
completely preserve hip bone strength during the 3-year intervention
period, whereas in the placebo group bone strength decreased
significantly in the study published in the journal Osteoporosis
International.
In the study, scientists at VitaK and the Cardiovascular Research
Institute (CARIM), both at Maastricht University, The Netherlands,
tested whether high vitamin K2 intake promoted bone mineral density
and bone strength. The double-blind, placebo controlled design
followed 325 apparently healthy, non-osteoporotic women for three
years and tested bone mineral content, femoral neck width (the most
common location for fracture) and bone mineral density at the
beginning and at the end of each year.
Results showed that supplemental vitamin K2 improved bone mineral
content and femoral neck width, but not bone mineral density. The
researchers concluded that vitamin K2 intake may contribute to
preventing postmenopausal bone loss.
"These findings are quite exciting," said lead author Leon J.
Schurgers, Ph.D. "Research has shown many indications that vitamin K
contributes to the maintenance of bone strength. Besides various
population-based studies and a number of clinical intervention trials
investigating the effects of increased vitamin K intake, it has also
been reported that subjects receiving vitamin K antagonists (oral
anticoagulant therapy) have lower bone mineral density and increased
fracture risk. Vitamin K2 has significant potential to benefit bone
health."
This study was conducted using menatetrenone, synthetic vitamin K2 as
MK-4. According to the authors, It should be realized, however, that
MK-4 has a very short biological half-life time (1-2 h), which
required that it was given three times daily in a dose of 15 mg per
helping. Even at this regimen its short half-life will result in
fluctuating K2 serum levels, which may explain the requirement of a
high dose. At this time no data are available on the efficacy of
MK-4 at lower doses, for instance in the range between 100-500
micrograms per day. A possible alternative to MK-4 might be using
natural menaquinone-7 (MK-7), the K2 vitamin most abundantly found in
the Japanese food natto (fermented soy beans). MK-7 has probably a
comparable effect as MK-4, but it has a halflife in the circulation
of 3 days, resulting in more constant plasma levels and accumulation
in the blood and various tissues. Therefore, MK-7 is the most logical
choice for use as a low-dose food supplement, because even at low
intake relatively high blood and tissue levels can be obtained.
Natural Vitamin K2 as menaquinone-7 (Mk-7) has been shown to be the
most absorbed, have the longest plasma half-life time and greatest
bioactivity throughout the whole body of any form of vitamin K. As a
result, and based upon population studies of vitamin K intake, it is
believed that just 45 mcg of menaquinone-7 (MK-7) daily will provide
optimal vitamin K status.
About MenaQ7(TM)
MenaQ7 provides Natural Vitamin K2 as an extract of natto, a
fermented soy food from Japan. Natto is particularly rich in the
highly bio-available form of vitamin K2 called menaquinone-7 (MK-7).
Natural Vitamin K2 also may provide significant benefit to skeletal
and cardiovascular health due to its roles in calcium utilization via
the promotion of vitamin K-dependant proteins.
For more information on the health benefits of MenaQ7, please visit
http://www.menaq7.com
About NattoPharma
NattoPharma, Norway is the exclusive international supplier of MenaQ7
Natural Vitamin K2 (Mk-7). NattoPharma has entered into a multi-year
Research and Development program to substantiate and discover the
health benefits of Natural Vitamin K2 for applications in the
exciting marketplace for functional food and health food
supplements.
For more information, contact Morten Sundstø at 950 61 860 or email
morten@sundsto.com
http://hugin.info/137386/R/1167186/228857.pdf
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