Date:   11/1/2007 8:11:20 AM ( 17 y ago)
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URL:   https://www.curezone.org/forums/fm.asp?i=1033139

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Selenium deficiency & schizophrenia
If you click on the link go to the map and it shows that New York State has the highest number of schizophreia cases. It is related to diet in some way according to the article.
http://books.google.com/books?id=Nh1XcxacpZoC&pg=RA4-PA519&lpg=RA4-PA519&dq=s...

Schizophrenia appears to be a syndrome, a spectrum of diseases that produce similar symptoms. It is argued that a significant group of schizophrenics, however, experience such symptoms because of selenium deficiency and that the disease is a member of the selenium family tree (Brown and Foster, 1996).

[paragraph omitted]

Further evidence to support the viewpoint that schizophrenia may be the member of the selenium family tree was provided by Brown (1994) who used two-by-two contingency tables to compare prevalence from nine U.S. schizophrenia surveys, conducted between 1880 and 1963, with crop selenium deficiency. This approach provided a significant correlation between low selenium and high schizophrenia states (p=0.0001; Yates corrected chi square). This research also demonstrated a significant correlation between low selenium and high schizophrenia in five or more of the nine surveys (p=0.0002). Indeed there is significant correlation between both the 1880 and1963 schizophrenia survey data and low selenium states.

Additional evidence of selenium deficiency came from Buckman and co-workers (1987), who measured levels of the seleno-enzyme glutathione peroxidase in blood samples taken from chronic schizophrenics and compare them with those found in a control group of non-schizophrenic mental patients. Buckman and colleagues discovered a strong, negative correlation in schizophrenics between glutathione peroxidase activity and computer tomography scan measures of brain atrophy and increased ventricle-brain ratios. That is, the lower the seleno-enzyme level, the greater the brain abnormalities. Such relationships did not occur in the control group, which suggest a unique relationship between selenium deficiency and the tissue damage found in the brains of schizophrenics.


The argument is not that selenium deficiency is not the sole cause of schizophrenia. Indeed, schizophrenia is probably a second or third order disorder that may also involve calcium and essential fatty acid deficiencies (Foster 1992). In fact, evidence to support this possibility has been provided by Templer and co-workers (1990) who have shown that in both the United States and Italy, significative positive correlations between schizophrenia and prevalence and mortality from cancer of the oseophagus. As argued earlier, cancer of the eosophagus is probably at least a third order disease, that has been preventable by both selenium and calcium supplementation Blot et al. 1994, Yu & Foster 1991).

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