Excessive????

It would be nice to know what exactly is excessive...but of course only those brave souls in the other forums will be able to tell us in a year or so....


1: Zhonghua Yu Fang Yi Xue Za Zhi. 1996 Nov;30(6):340-2.Links
[Experimental studies on effects of excessive Iodine intake on
morphology and function of kidney in mice][Article in Chinese]


Zhou X, Yin G.
Department of Biochemistry, Hebei Medical College, Shijiazhuang.

To understand that if excessive Iodine can cause damage to tissues
other than thyroid gland, mice were fed with iodine-excess water and
iodine-excess goiter was caused in them. Hisitomorphology and
function of the kidney, in addition to the thyroid gland, in goiter
mice were observed. Results showed that two hundred days after being
fed with 3,000 micrograms Iodine per liter water, in addition to
causing iodine-excess goiter characterized with proliferation of
large amount of colloid in thyroid follicles, morphology and function
of the kidneys in mice were significantly damaged, with prominent
pathomorphological changes of crescent formation and metabolic
inhibition in microsome membrane Na(+)-K(+)-ATPase activities in
their kidneys. Na(+)-K(+)-ATPase activities were 21.95 +/- 7.50
mumolPi/mg Pr.hr in low iodine group, and 17.64 +/- 8.63 mumolPi/mg
Pr.hr in excessive iodine group, with significant difference. It
suggests that excessive iodine can cause damage not only to thyroid,
but to the whole body.

PMID: 9388908 [PubMed - indexed for MEDLINE] Tweet