I am a representative for M****tech . I have worked with about a few thousand clients over the last 5 years. We some some people (most often children & young adults) respond in an where from a few days to 2 months. Many adults over age 30 will often not see significant improvement for 3-6 months. It also often helpful to take a therapeutic amount for a health challenge. I highly recommend Dr. Schlacter's book, In Search of Manna.