I tend to be the opposite of everyone. I'm a thin hypothyroid. I tend to be low in copper while others seem to be high. I tend to be high in magnesium, while others tend to be low. And, I tend to be sensitive to MSM while others can swim in it. I want to take it so bad, but eventually I always seem to react. Moly helped, but I still can't take MSM like others. 500mg once or twice a week is my max, and then it is usually good if I skip a week. And I'm fairly certain it isn't detox, as I don't get any other detox symptoms(which I have gotten with other cleanses), I only get an aggravation of my interstitial cystitis.
So, you shouldn't have any problems. Listen to your body, and you will be fine.