Last year my Father died of Prostate Cancer. He had contracted a fungus under his toe-nails, for about the last year before he died. I would take my pedicure-kit to his home and would soak his feet, and really give him a good 'pedicure' with soothing lotion, and buffing his feet. (a real treat for him) About 6-months ago, I noticed one of my big-toe nails began to turn dark, with white patchy places on it.(something I thought I 'caught' from my Dad)... Well, I did not know what to do, so I did nothing. (I keep polish on my nails 'always' so I kinda forgot about it) As you know I have been on 'your protocal" for about a month now, and when I took the polish off last night to re-apply, I noticed I HAVE NEW NAIL GROWTH about half way up my nail !!! So, something is working. As for the pain in my back, and knee, it is less painful, but STILL there. I am up to 1-teaspoon on MSM in the morning and another at night.(mixed with liquid Vit. -C) (2-tsp. per day) Can you suggest what could be wrong? Shouldn't the pain be gone by now? Upon listening to the tape, some people started out with a high-dose, but, I started out with 1/4 tsp. Any suggestions?