What does/do your doctor(s) diagnose,... and the prognoses?

Your history of so many complaints and the multiple beneficial results that you're having sounds quite complicated, but is consistent with many other patients' stories of their benefits from A*****ose.  ie  Often, I see a patient taking nutraceuticals for cancer (or such) and after a few months, it may be inconclusive that their cancer is improving, but their arthritis subsides, or asthma, or their insulin requirement is considerably reduced, so that they are enthusiastic about continuing.  If the immune and repair systems get the support they need, they may turn around terminal illnesses even during the last stages before death.   That is what I think....and know from many observations.  

Are you taking a good multivitamin with minerals, phytonutrients, immune stimulators, etc as well?  The body has many nutritional requirements and a deficit in any of them causes problems or suboptimal operation in systems. 

a pudendal nerve problem which compresses my nerve and is causing nerve damaged so it causes pain in my vulva. I have been getting pain or 13 years but the pain has worsened the past 4 years.

Is this a result of childbirth or other injury?  Or is it more of a neuropathy?  If it is from an injury, have you tried a chiropractic workup, preferably by a DC who specializes in neurological problems?  In general, they also tend to be much more open to the nutraceutical approach than MDs.  (Just like with MDs, you may need to shop around to find a good one.)

each time the time with no pain in between gets longer - first it was 6 days, then 11, then, 14 and this last time 23 days.

That is wonderful.  Was it occurring before you increased PLUS?  I see nothing so far in your narrative that the detox symptoms have had accompanying benefits, that you were not experiencing before the increase. 

I am also of the inclination that if something is helping me, I can endure a lot of discomfort as long as there is a goal and I expect that there will be an end to the suffering.   I am not doctrinaire believing that you must suffer to make progress (No pain, no gain!) and that medicine should taste bad.  This is not physical exercise that you must push yourself to your limit of endurance or pain tolerance so that your limits and capabilities grow and extend to new levels. 

Meanwhile, I am glad for you that you have eliminated so many problems and are still improving in the others.  Pay attention to what is working.  Observe and adjust.  I suggest that you set yourself time periods to follow a regime, then evaluate your results and adjust as indicated for a next time period. 

Generally in this life, pain is unavoidable, suffering is optional. If you have a sense that the increased detox suffering is accelerating your recoveries in your other problems, then I would say, "Go for it!"

musashi