In the context of energy exchanges and molecular products, it can often excede human understanding. The factors involved [from simple-celled metabolism] which affect the mammalain physiology are so enormous it can give me a brain cramp. Even simple hormonal products can be beyond the comprehension even the maddest scientists! Just look at the pharmaceudicals which can influence simple cell receptors.
The moral of the story is; never underestimate these little critters.
Now, having said that, I think I see your point. Ya sort of have to start by using a philosophy of simplicity. What do they do? Why do they do it? ect. Shroom