Hmm....in addition to the liver support, the milk thistle is an anti inflammatory, so not sure why it would be bothering your wrist, usually side effects are in the gut with it, I think. You have been under a lot of stress with the tests, so it could be a meltdown...
I have begun eyeing any change for the worse as temporary and working towards the betterment of the condition. Every once in awhile I will get an odd detox reaction out of the blue after weeks of feeling fabulous and figure there is another layer being peeled back and worked on.
Have you tried lightly rotating or stroking the wrist while pulling? Maybe there is inflammation around the area. I think bfmatthews had a TERRIBLE couple nights with her feet before they stopped bothering her, have not heard from her lately how she is doing. A couple people I know suffered a detox reaction when they switched to the olive, even after being on another oil for so long. My office mate's knee is a lot better, although he is want to say if it is from pulling or the stretching he is doing WHILE pulling with the olive. He was on the sesame for about 6 weeks before that with no change to the knee.
I wonder if the milk thistle actually stirs things up in the liver, rather than just helps support it? How long have you been on it?
Sorry you are feeling bad. Slap some footpads on at night if you got any...they really help me through detox reactions.