I've had migraines for atleast a couple years and they stopped around my seventh flush. The migraines and the constipation went away at the same time. I had also started Oxypowder at that time. That helped keep the colon clean inbetween flushes and home colonics. I have to say the home colonics deserve a lot of credit for that because I got out some very thick & toxic stuff. It looked like coffee graines and mucous & all sorts of nasties that were making me very unhealthy.