I've been on candid supps for a while now. I had terrible die-off from Primal Defense and noticed lower right back after taking it (about 6 weeks ago). Quit taking it, but the back pain continued to some degree. Started Threelac two weeks ago - no noticeable die-off, but last night started getting sharp pains under right side of my rib cage, gall bladder? That stopped after about a half hour than terrible lower back pain. Went to emergency today and the doc says muscle spasm? To me, I think it could be my kidney - from die-off. Could all the toxins being killed and released be causing pain in my kidney. It's at the very lower right side, probably below pelvis. There was a trace of blood in the urine, but the doctor said that was of no concern. Any help? I've been very constipated for weeks now. Thanks so much, getting worried here.