NO JUST THE FIRST THIS IN THE MORNING. JUST BE CLOSE TO THE TOILET.WITHIN 1 TO 2 HOURS YOU WILL BE RUNNING FREQUENTLY TO THE BATHROOM. FOR ABOUT AN HOUR. THEN YOUWILL BE DONE. I LIKE THIS BECAUSE MY ANUS DOES NOT BURN LIKE SOME OF THE OTHERS LIKE MAGNESIUM CITRITRATE(COKECLASSIC) I SLAT WATER IN PLACE OF THIS.