I'm so sorry you are going through this. I know the hell it can be (and still is for me). I wouldn't just think about using Isocort "if all else fails". It would be one of the FIRST things I would try. It has been extremely effective for me (at least made it possible to function for portions of the day). Bezwecken is the best brand (it may be the ONLY brand....but there are a lot of different looking labels...... so I would be sure that it SAID Bezwecken on it (they developed it).