I know what you mean. I have tried everything and sometimes something works for a while and then stops. I hate to think of the money I have spent over the years because of this problem. I am so envious of people whose body systems just work normally no matter what they eat while I have to go to bed every night wondering whether I will go the next day and the next......Every night I take my regimn of metimusel, kolinade and mineral oil. Sometime it works a bit, and other times it doesn't work at all. Even laxatives sometimes don't work and I have to continue to repeat them the next day and perhaps the next day again. It is so frustrating and often it is all I can think about. I am afraid to eat to much because it does not seem to be moving properly through me and just gets stopped. So frustrating and upsetting.