With the use of colosan you are making fluids, rather than removing them; oxygen combines with hydrogen and forms water. Colosan is not a laxative that removes minerals from the body. I don't see the necessity to take something else in order to take care of a side effect that it (Colosan) doesn't have.
Having said this, your ideal is to come to a point of not needing such aids in the long run. After a while, take no more than 1-2 times per week, and then be pretty much without it. You will want the to do its job without having to rely on crutches.