Hi Sedonia....yes, colonics are great, I do those too. I start to feel sick with parasite or bowel cleansing if I don't. I don't know which type of Colon Cleanse is best for me yet, I'm still experimenting. I have removed some plaque before using just P&B, but felt very congested and constipated, and so I went off it. I've tried magnesium oxides which got things moving well, but I didn't think it was liquifying plaque. I don't know, others seem to find it good though. I'm on the schulze intestinal formulas now and I like them. It's been about 10 days, I haven't seen plaque yet, but I'm at a slow pace and building slow. I've learned from past trials that with any cleansing I do, I have to go slow and build, otherwise the panic starts. It is a challenge to get the plaque out though while there's a lot of parasites, they kick up a real fight. I'll post how it goes.