If you have kidney problems, I highly recommend doing a kidney cleanse while you are chelating. I use DR Clarks kidney cleanse My favorite part of it is the tea made with three herbs: Gravel root, marshmallow root, and hydrangea root. I took it about a week into chelation, and I instantly felt the difference. It was like putting a week of chelation into 1. Still, when I take the tea, it boosts the effectiveness of the DMSA. DMSA is filtered through the kidneys, so it is super important to keep the kidneys clear during chelation. I also use intestinal binders like clay and zeolite, because the intestines can take a burden off the kidneys..