Slowsmile, Thank you for your reply. It took me forever to find out how to open my msg to my question. I still don't know if I'll be able to do it again. It isn't user friendly to get to my in box and see the specific reply to my question. Ok thank you again for sending me the amounts to take. My question is for milk thistle. I found some online for 4500 mg and you wrote 450 mg. Did you maybe make a mistake & meant 4500 mg?