Re: Vitamin A IMPORTANT for synthesis of adrenal and thyroid hormones

The gene polymorphism you're looking for is BCMO1.
I am homozygous (++) and found this out after my spectracell showed a significant vitamin A deficiency and tried to reverse engineer why it was happening. This was around the time when I started to get blurred vision and night blindness.
In all honesty I am still working on whether there are additional reasons. One could very well be adrenal fatigue which I have had for years because of PTSD. I also recently found out that vitamin A is a cofactor in converting cholesterol to pregnenolone, the mother hormone, which also produces cortisol. So, theoretically, a low conversion from BetaCarotine (in vegies) to retinol (true Vit a) could cause a lack of ability to deal with stress. So, stressed and wired people could indeed have this as a potential genetic reason...

Run your raw 23andme data through "sterling" service and go to the "Eye Health" section and see the results for the following three genes:
BCMO1 rs4889294
BCMO1 R267S rs12934922
BCMO1 A379V

Read more about it by looking at the article from selfhacked from google search results on keywords "importance-real-vitamin-retinol" (with the quotes). It's currently the first search result... I am not allowed to post a link here...


I hope this helps someone... Tweet