I know this thread is six years old but in case some one comes upon it through research, I just wanted to report that Ubiquinol gave me nasty headaches for almost a week. No nausea though. Despite the headaches, I did have more energy so I kept taking the Ubiquinol, hoping the reaction was some sort of detox. Apparently it was. Within about 5 days the headaches disappeared and I just felt fabulous.