Candida Albicans biofilms can be disrupted. One of the main elements doing it is water. Glucose is soluble in water. Candida biofilm matrix is mostly glucose. This is the reason because enemas to irrigate the colon dissolve candida albicans niche.
Moreover, antifungal synergistic combinations disrupt biofilms. I have posted about substances that have been proved to disrupt candida biofilm matrix. Yes, single antifungal therapy isn't effective against candida infections.
Glucose dissolves in water due to the polar water molecules attached to the glucose molecules. The numerous O-H (hydroxyl-) groups in glucose are normally attracted to the water molecules by dipole-dipole forces. The force's strength can be greater compared to the glucose -glucose interactions. The hydrogen bonding between water molecules and glucose as well as makes the glucose more water soluble.