Just started taking Idoral 12.5 mg 10 days ago. Wasn't sure just how much to take a day so been taking 1 in morn and 1 at night. Total of 25mg/daily. Have had very little detox symptoms-just a very minor frontal headache. My sinuses seem to be better than they have been in years and seem to have a good energy boost so far. The main reason to try this was that i was constantly tired and my PSA lvl.s were through the roof. Hope this is what some say it's cracked up to be as so far so good. Yes am taking the other support mechs with the "I"