Have you ever gotten a hair test? From the 200 or so I've seen along with symptom history it seems that when a person has hi-norm or higher cadmium the person also has symptoms of ADD (often inattentive form) and or catecholamine depression.
I am one such person. I also have/had bone density problems in my early 40's where the endocrinologist did not know why. He never asked about my exposure to lead and cadmium in renovation construction since childhood.
After 1.5 yrs of Cutler Protocol chelation many symptoms are better. I've just gone off the ADD meds and am just using supplements--tyrosine, LDopa, glutamine, etc along with cat. cofactors (mostly from a multi v.). I have to take them about 4-5 x per day to get a smooth effect but use low doses.
This supplement has been working nicely for the cat Depression --lethargy, butt stuck to the sofa, etc.