Anti-septicaemic effect of polysaccharide from Panax ginseng by macrophage activation.
" These results suggest that PS from Panax ginseng possess a potent anti-septicaemic activity by stimulating macrophage and a potentiality as an immunomodulator against sepsis occurred by Staphylococcus aureus."
Susceptibility of some clinical isolates of Staphylococcus aureus to bioactive column fractions from the lichen Ramalina farinacea (L.) Ach.
"The antimicrobial activities of two bioactive column chromatographic fractions (RF1 and RF2) from the lichen Ramalina farinacea (L.) were evaluated against 15 clinical isolates of Staphylococcus aureus. The susceptibility pattern of the isolates towards tetracycline (TCN) and ampicillin (AMP) was similarly -evaluated for comparison purposes. The results show that RF1 and RF2 with an MIC(90) ( minimum -inhibitory concentration against 90% of the isolates) of 535.5 and 317 microg/mL respectively, performed generally better than TCN and AMP with an MIC(90) of 976.5 and 357 microg/mL respectively."
Effects of some plant extracts and Antibiotics on Pseudomonas aeruginosa isolated from various burn cases.
"CONCLUSION: Pseudomonas aeruginosa was the predominant bacterial isolate followed by Staphylococcus aureus, then other type of bacterial was isolated in various percentage from each tetracycline covered burns and non-tetracycline covered burns. Most concentrations of the extracts of the studied plants showed a high antibacterial activity against Pseudomonas aeruginosa, and showed significant differences between susceptibility of Pseudomonas aeruginosa isolated from each tetracycline covered burn and non-tetracycline covered burn."
Antibacterial activity of calozeyloxanthone isolated from Calophyllum species against vancomycin-resistant Enterococci (VRE) and synergism with Antibiotics .
"Calozeyloxanthone ( 1) was re-isolated from the root bark of Calophyllum moonii, an endemic species of Sri Lanka, and found to be active against vancomycin-resistant Enterococci (VRE) and vancomycin-sensitive Enterococci (VSE) with MIC values of 6.25 microg/ml and 12.5 microg/ml, respectively."
A review on usnic acid, an interesting natural compound.
"Usnic acid is one of the most common and abundant lichen metabolites, well known as an antibiotic, but also endowed with several other interesting properties."
"Both the (+) and (-) enantiomers of usnic acid are effective against a large variety of Gram-positive (G+) bacterial strains, including strains from clinical isolates, irrespective of their resistant phenotype. Of particular relevance is the inhibition of growth of multi-resistant strains of Streptococcus aureus, enterococci and mycobacteria. The (+)-usnic acid enantiomer appears to be selective against Streptococcus mutans without inducing perturbing side effects on the oral saprophyte flora."
Antibacterial, antifungal activities of Barringtonia asiatica.
"The crude methanolic extract of Barringtonia asiatica (leaves, fruits, seeds, stem and root barks) and the fractions (petrol, dichloromethane, ethyl acetate, butanol) exhibited a very good level of broad spectrum antibacterial activity. A number of fractions demonstrated antifungal activity against a number of fungi."
[Pharmaceutical importance of Allium sativum L. 2. Antibacterial effects]
"The communication summarizes mainly newly obtained experimental findings confirming the antibacterial effect of garlic preparations (powders, extracts, juice, essential oil, oil macerate) and their individual components."
Marked potentiation of activity of beta-lactams against methicillin-resistant Staphylococcus aureus by corilagin.
"We found that an extract of Arctostaphylos uva-ursi markedly reduced the MICs of beta-lactam Antibiotics , such as oxacillin and cefmetazole, against methicillin-resistant Staphylococcus aureus. We isolated the effective compound and identified it as corilagin. Corilagin reduced the MICs of various beta-lactams by 100- to 2,000-fold but not the MICs of other antimicrobial agents tested. The effect of corilagin and oxacillin was synergistic. Corilagin showed a bactericidal action when added to the growth medium in combination with oxacillin."
Inhibition by the essential oils of peppermint and spearmint of the growth of pathogenic bacteria.
"The effects of the, essential oils of peppermint (Mentha piperita L.), spearmint Mentha spicata L.) and Japanese mint (Mentha, arvensis L.), of four major constituents of the esssential oil of peppermint, and of three major constituents of the essential oil of spearmint, on the proliferation of Helicobacter pylori, Salmonella enteritidis, Escherichia coli O157:H7, methicillin-resistant Staphylococcus aureus (MRSA) and methicillin sensitive Staphylococccus aureus (MSSA) were examined. The essential oils and the various constituents inhibited the proliferation of each strain in liquid culture in a dose-dependent manner. In addition, they exhibited bactericidal activity in phosphate-buffered saline. The antibacterial activities varied among the bacterial species tested but were almost the same against antibiotic-resistant and antibiotic-sensitive strains of Helicobacter pylori and S. aureus. Thus, the essential oils and their constituents may be useful as potential antibacterial agents for inhibition of the growth of pathogens."
A current review of the antimicrobial activity of Hypericum perforatum L.
(Your favorite Taggy, St. Johnswort)
"A petrolether extract of the areal parts of Hypericum perforatum L. was reported to be active against gram-positive bacteria. Hyperforin, a phloroglucin derivative was shown to be the antimicrobial principle. Hyperforin exhibited an excellent effect against methicillin-resistant strains of Staphylococcus aureus with a MIC value of 1.0 microg/ml. A butanol fraction of St. John's Wort revealed anti-Helicobacter pylori activity with MIC values ranging between 15.6 and 31.2 microg/ml. Recently, hydrous solutions of Hypericum perforatum teas were found to be antimicrobially effective against gram-positive bacteria with special activity towards methicillin-restistant strains of Staphylococcus aureus (MIC values: 1.3 to 2.5 mg herb/ml)."