The Truerife F-117 is basically an EMEM type of plasma device. Controlled by an Atelier Robin programmable frequency generators similar to the f165. I can use the True Rife programs on my f165 - EMEM3D set up. And my f165 alone could be as good or better than the GB 4000.
I don't know if the Truerife plasma device is better or worse than others. EMEM's are high voltage devices that have a typical frequency range of 0 - 10,000 Hz. Looks like a good EMEM unit though.
You should read some of these testimonials of how these Rife like lyme machines work to help make a better choice. These reviews are years old so the f165 is not included to compare. I hope this doesn't confuse you too much.